Advanced DSEK / DSAEK Corneal Transplant Surgery
FDA Approved
Advanced Technology
At a Glance
Quick facts about DSEK / DSAEK (Endothelial Keratoplasty) to help you understand the basics
- Treatments offered
Descemet’s Stripping Endothelial Keratoplasty (DSEK / DSAEK)
- Finance
Transparent pricing and full aftercare support; financing options discussed during consultation
- Why Choose
Pioneers in corneal transplant surgery using advanced endothelial grafting techniques and precision donor preparation for superior outcomes.
- Locations
London, Sussex, Surrey
Key Benefits
- Targeted corneal layer replacement
- Minimally invasive transplant
- Improved visual clarity
- Reduced rejection risk
- Shorter rehabilitation
- Consultant-led expertise
What is DSEK / DSAEK?
DSEK (Descemet’s Stripping Endothelial Keratoplasty) and DSAEK (Descemet’s Stripping Automated Endothelial Keratoplasty) are partial-thickness corneal transplant procedures used to treat diseases affecting the endothelial layer; the thin, innermost part of the cornea responsible for pumping out excess fluid and maintaining clarity.
When this layer fails (as in Fuchs Endothelial Dystrophy, pseudophakic bullous keratopathy, or post-surgical endothelial damage), the cornea becomes swollen and vision cloudy.
Unlike traditional full-thickness transplants, DSEK and DSAEK replace only the diseased inner layer, leaving the outer corneal structure intact. This results in faster recovery, reduced rejection risk, and more stable visual outcomes.
Types of Corneal Transplant Techniques
1
DSEK (Descemet’s Stripping Endothelial Keratoplasty)
The traditional technique where the damaged inner layer is manually removed and replaced with healthy donor endothelium. This approach offers excellent clarity and a smaller incision than full-thickness grafts.
2
DSAEK (Descemet’s Stripping Automated Endothelial Keratoplasty)
3
DMEK (Descemet’s Membrane Endothelial Keratoplasty)
The most refined approach, transplanting only the ultra-thin endothelial membrane for the fastest recovery and most natural vision, ideal for suitable eyes with clear outer corneas.
Comparing Transplantation Procedures
Please note that your consultant will recommend the most suitable treatment option tailored to your specific case.
Procedure Type
How it works
Best For
Pros
Cons
Procedure Type
DSEK
How it works
Replaces the damaged inner corneal layer with donor endothelium
Best For
Fuchs Dystrophy, corneal swelling
Pros
Smaller incision; faster recovery than full graft
Cons
Slightly thicker donor tissue than DMEK
Procedure Type
DSAEK
How it works
Automated version of DSEK using precision donor preparation
Best For
Moderate-to-severe endothelial failure
Pros
Smooth donor interface; reliable outcomes
Cons
Rare need for repositioning if graft dislocates
Procedure Type
DMEK
How it works
Transplants only Descemet’s membrane and endothelium
Best For
Clear outer corneas; advanced endothelial disease
Pros
Fastest recovery; sharpest vision
Cons
Technically demanding; not suitable for all patients
What are the Benefits and Risks of DSEK / DSAEK?
Your consultant will provide a personalised risk-and-benefit discussion based on your eye’s specific needs.
Benefits (vary by procedure):
Restores clear vision with minimal tissue replacement
Smaller incision and faster recovery than full-thickness grafts
Lower risk of graft rejection
Proven outcomes for Fuchs Dystrophy and similar conditions
Risks/side effects (not exhaustive):
Temporary blurring as the graft settles
Rare graft dislocation requiring repositioning
Minimal risk of infection or rejection
Need for glasses or lens adjustment post-surgery
Not Sure If You're Eligible?
Book a comprehensive eye examination to better understand your vision and available treatment options.
Am I Suitable for DSEK / DSAEK?
Your surgeon will speak with you about the benefits and risks involved before your procedure.
You may be suitable for DSEK or DSAEK if you have:
Fuchs Endothelial Dystrophy, causing corneal swelling, glare, and cloudiness
Pseudophakic bullous keratopathy (corneal swelling after cataract surgery)
Endothelial decompensation due to trauma, ageing, or previous surgery
Suitability depends on the overall health of the outer cornea, retinal function, and ocular surface. A thorough diagnostic evaluation at Centre for Sight will determine which transplant method is right for your eyes.
Costs and Finance Options
Please contact us to obtain your personalised quote. Graft technique, donor tissue type and complexity influence cost.
Additional Procedures
DALK
Bespoke Price
Per Eye
Consultant-led surgery
Advanced diagnostics and treatment planning
Laser-assisted procedure
24-hour emergency support
Comprehensive care package
1-year follow-up care
DSAEK
Bespoke Price
Per Eye
Consultant-led surgery
Advanced diagnostics and treatment planning
Laser-assisted procedure
24-hour emergency support
Comprehensive care package
1-year follow-up care
DSEK
Bespoke Price
Per Eye
Consultant-led surgery
Advanced diagnostics and treatment planning
Laser-assisted procedure
24-hour emergency support
Comprehensive care package
1-year follow-up care
Flexible Financing Options
Private Medical Insurance
Many of our Consultants work with all the major insurance providers*
Self Pay
Pay in full for patients who prefer a straightforward approach
0% APR Financing
6-24 month payment plans with approved credit
Military Discount
5% discount for active military and veterans
*Private Medical Insurance is unlikely to cover Laser Eye Surgery Procedures, Implantable Contact Lenses, or Laser Lens Replacement
FAQs
Find answers to frequently asked questions about DSEK / DSAEK, recovery, and what to expect from treatment.
What’s the difference between DSEK and DSAEK?
How long will recovery take?
Most patients notice clearer vision within a few weeks, with stability improving over several months as the graft fully integrates.
Will I feel pain during the surgery?
No. The procedure is performed under local anaesthesia with sedation — patients are comfortable throughout.
What happens if the graft detaches?
In a small number of cases, the graft may need to be reattached with a simple air bubble procedure, often done in-clinic.
Why choose Centre for Sight?
Our corneal surgeons are leaders in partial-thickness transplant surgery, performing hundreds of successful grafts using the latest endothelial techniques with proven long-term results.
What aftercare should I follow after DSAEK?
For information relating to aftercare please follow the guidelines in our aftercare booklet.
Have Questions?
Our patient care team is here to answer any questions you may have.
Patient Success Stories
A first class experience
The whole process, start to finish, is first class. The facility at East Grinstead is superb and the staff were friendly and professional. The consultant, Saj Khan, is fantastic, a great communicator as well as being a leader in his work.
I had replacement lenses, after 3 months they became a little cloudy, distorting my vision. This is a known problem. I booked a consultation, within 2 hours I had been assessed and had laser treatment. No fuss, no problem, job done.
Laser Lens Replacement
Richard Black
Lens Replacement with Mr Shahnazaryan
The staff, experience and ultimately the outcome is why I have given this review a 5star. Mr David Shahnazaryans manner and expertise is outstanding. Whilst in the theatre Dr Lam kept me relaxed and comfortable with her kindness and fantastic professionalism. All the staff at CFS from the admin team, reception, clinic and theatre were excellent. I recommend them to everyone.
Laser Lens Replacement
Laser Lens Replacement
karen ryan
Laser lens replacement with trifocal lenses
I had Laser lens replacement with trifocal lenses for both eyes and the results are just amazing. The thorough testing and information I received pre and post operative was excellent. I highly recommend Mr Sheraz Daya who in my opinion is an “eye god” his lovely wife and highly professional team to anyone seeking this type of surgery.
Laser Lens Replacement
Susan Gifford
Professional Actor
5* Lens Replacement Procedure
I had tri focal lens replacement, both eyes done on the same day by Mr Daya. I wish I’d had it done sooner, it’s totally life changing. I researched the procedure for many months and selected Centre for Sight and I’m so glad I did. The whole process is first class from the very first contact, the initial tests could not be more thorough and the procedure is totally painless. The whole team could not be more helpful, I cannot praise them enough. I have perfect all round vision now so if you’re considering having the procedure done then this is definitely the place to choose you won’t regret it
Laser Lens Replacement
Jayne Chandler
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